Humankind's greatest infectious threats are posed by viruses. Even before COVID-19 made a global impact on health and economies, Dengue and West Nile Virus have long been endemic threats in warmer parts of the world and Zika emerged as a local threat in South America. As climate change drives insect migration, these viruses may soon pose a threat outside their current ranges.
Protinhi have a new approach to developing treatments for these viral diseases, with a program leading on Dengue. Viruses replicate within a host cell after infection using a virally encoded protease. These proteases present a target for Protinhi's innovative small molecule compounds that inhibit this process, blocking viral replication.